021 Cromer Blood Group
The Cromer blood group system consists of 16 antigens carried on a GPI-linked glycoprotein (DAF, CD55) that consists of 481 amino acids. It has a leader sequence of 34 amino acids and a GPI motif of 28 amino acids, both of which are cleaved from the membrane bound protein.
Antigens
[1] Cra
[2] Tca
[3] Tcb
[4] Tcc
[5] Dra
[6] Esa
[7] IFC
[8] WESa
[9] WESb
[10] UMC
[11] GUTI
[12] SERF
[13] ZENA
[14] CROV
[15] CRAM
[16] CROZ
[17] CRUE
[18] CRAG
[19] CROK
[20] CORS
Reference Info
Gene: CD55
Allele: CROM*01. Acceptable: CR*A, or Cra if inferred by haemagglutination
Seq: NG_007465.1 (genomic), NM_000574.3 (transcript)
Entrez GeneID: 1604
Number of exons: 11
Allele: CROM*01. Acceptable: CR*A, or Cra if inferred by haemagglutination
Seq: NG_007465.1 (genomic), NM_000574.3 (transcript)
Entrez GeneID: 1604
Number of exons: 11
Loading Data ... |
allele_category | Phenotype | Allele Name | Nucleotide Changes |
Exon | Amino Acid Changes |
hg38 | gnomAD | rsNum | GenBank | Reference |
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0:Antigen Alleles | CROM:-1 or Cr(a-) | CROM*-01 | c.679G>C | Exon 6 | p.Ala227Pro | chr1:207331122 | ||||
0:Antigen Alleles | CROM:1 or Cra+) | CROM*01 or CR*A | ||||||||
0:Antigen Alleles | CROM:-5 or Dr(a-) | CROM*01.-05 | c.596C>T | Exon 5 | p.Ser199Leu | chr1:207326769 | ||||
0:Antigen Alleles | CROM:-6 or Es(a-) | CROM*01.-06 | c.239T>A | Exon 2 | p.Ile80Asn | chr1:207322520 | ||||
0:Antigen Alleles | CROM:-10 or UMC- | CROM*01.-10 | c.749C>T | Exon 6 | p.Thr250Met | chr1:207331192 | ||||
0:Antigen Alleles | CROM:-11 or GUTI- | CROM*01.-11 | c.719G>A | Exon 6 | p.Arg240His | chr1:207331162 | ||||
0:Antigen Alleles | CROM:-12 or SERF- | CROM*01.-12 | c.647C>T | Exon 5 | p.Pro216Leu | chr1:207326820 | ||||
0:Antigen Alleles | CROM:-13 or ZENA- | CROM*01.-13 | c.726T>G | Exon 6 | p.His242Gln | chr1:207331169 | ||||
0:Antigen Alleles | CROM:-14 or CROV- | CROM*01.-14 | c.466G>A | Exon 3 | p.Glu156Lys | chr1:207324738 |
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0:Antigen Alleles | CROM:-15 or CRAM- | CROM*01.-15 | c.740A>G | Exon 6 | p.Gln247Arg | chr1:207331183 |
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0:Antigen Alleles | CROM:-16 or CROZ- | CROM*01.-16 | c.389G>A | Exon 3 | p.Arg130His | chr1:207324661 | ||||
0:Antigen Alleles | CROM:3 or Tc(b+) | CROM*01.03 | c.155G>T | Exon 2 | p.Arg52Leu | chr1:207322436 | ||||
0:Antigen Alleles | CROM:4 or Tc(c+) | CROM*01.04 | c.155G>C | Exon 2 | p.Arg52Pro | chr1:207322436 | ||||
0:Antigen Alleles | CROM:8 or WES(a+) | CROM*01.08 | c.245T>G | Exon 2 | p.Leu82Arg | chr1:207322526 | ||||
4:Null Alleles | CROM:-7 or Inab | CROM*01N.01 | c.261G>A | Exon 2 | p.Trp87* | chr1:207322542 |
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4:Null Alleles | CROM:-7 or Inab | CROM*01N.02 | c.263C>A | Exon 2 | p.Ser88* | chr1:207322544 |
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4:Null Alleles | CROM:-7 or Inab | CROM*01N.03 | c.508C>T | Exon 4 | p.Arg170* | chr1:207325651 | ||||
4:Null Alleles | CROM:-7 or Inab | CROM*01N.04 | c.366_367insA | Exon 3 | p.Thr123Asnfs*6 | chr1:207324638 |
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