026 JMH Blood Group
The JMH blood group system consists of six antigens carried on a GPI-linked glycoprotein (CD108, Semaphorin, SEMA7A) that consists of 656 amino acids. It has a leader sequence of 44 amino acids and a GPI motif of 19 amino acids, both of which are cleaved from the membrane bound protein.
Reference Info
Gene: SEMA7A
Allele: Preferred: JMH*01. Acceptable: JMH if inferred by haemagglutination
Seq: NG_011733.1
(genomic), NM_003612.3 (transcript)
Entrez GeneID: 8482
Number of exons: 14
Allele: Preferred: JMH*01. Acceptable: JMH if inferred by haemagglutination
Seq: NG_011733.1
(genomic), NM_003612.3 (transcript)
Entrez GeneID: 8482
Number of exons: 14
| Loading Data ... |
| allele_category | Phenotype | Allele Name | Nucleotide Changes |
Exon | Amino Acid Changes |
hg38 | gnomAD | rsNum | GenBank | Reference |
|---|---|---|---|---|---|---|---|---|---|---|
| 0:Antigen Alleles | JMH:1 or JMH+ | JMH*01 | ||||||||
| 0:Antigen Alleles | JMH:-2 or JMHK- | JMH*01.-02 | c.619C>T | Exon 6 | p.Arg207Trp | chr15:74417377 |
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| 0:Antigen Alleles | JMH:-3 or JMHL- | JMH*01.-03 | c.620G>A | Exon 6 | p.Arg207Gln | chr15:74417376 |
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| 0:Antigen Alleles | JMH:-4 or JMHG- | JMH*01.-04 | c.1379G>A | Exon 11 | p.Arg460His | chr15:74411928 |
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| 0:Antigen Alleles | JMH:-5 or JMHM- | JMH*01.-05 | c.1381C>T | Exon 11 | p.Arg461Cys | chr15:74411926 |
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| 0:Antigen Alleles | JMH: -6 or JMHQ- | JMH*01.-06 | c.1040G>T | Exon 9 | p.Arg347Leu | chr15:74414893 |
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