024 OK Blood Group
The OK blood group system consists of 3 antigens carried on a single pass type I membrane glycoprotein with 2 IgSF domains called Basigin (aka CD147, neurothelin, EMMPRIN). It consists of 248 amino acids and has a leader sequence of 21 amino acids, which is cleaved from the membrane bound protein.
Reference Info
Gene: BSG
Allele: OK*01. Acceptable: OK*A, or Oka if inferred by haemagglutination
Seq: NG_007468.1
(genomic), NM_198589.2 (transcript)
Entrez GeneID: 682
Number of exons: 7
Allele: OK*01. Acceptable: OK*A, or Oka if inferred by haemagglutination
Seq: NG_007468.1
(genomic), NM_198589.2 (transcript)
Entrez GeneID: 682
Number of exons: 7
| Loading Data ... |
| allele_category | Phenotype | Allele Name | Nucleotide Changes |
Exon | Amino Acid Changes |
hg38 | gnomAD | rsNum | GenBank | Reference |
|---|---|---|---|---|---|---|---|---|---|---|
| 0:Antigen Alleles | OK:-1 or Ok(a-) | OK*01.-01 | c.274G>A | Exon 3 | p.Glu92Lys | chr19:580428 |
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| 0:Antigen Alleles | OK:-2 or OKGV- | OK*01.-02 | c.176G>T | Exon 2 | p.Gly59Val | chr19:579608 |
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| 0:Antigen Alleles | OK:-3 or OKVM- | OK*01.-03 | c.178G>A | Exon 2 | p.Val60Met | chr19:579610 |
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| 0:Antigen Alleles | OK:1 or Ok(a+) | OK*01.01 |