Blood Group Database

030 RHAG Blood Group

The RHAG blood group system consists of three antigens carried on a multipass membrane glycoprotein called RhAG (Rhassociated glycoprotein; aka CD241). It consists of 409 amino acids and both amino and carboxyl termini are predicted to be intracellular.

Antigens

[1] Duclos

[2] Ola

[3] DSLK†

[4] …

[5] §

Reference Info

Gene: RHAG
Allele: RHAG*01
Seq: NG_011704.1

(genomic), NM_000324.2

(transcript)
Entrez GeneID: 6005

Number of exons: 10

RHAG

Loading Data ...

allele_category	Phenotype	Allele Name	Nucleotide Changes	Exon	Amino Acid Changes	hg38	rsNum
0:Antigen Alleles	RHAG:4	obsolete as of 2018, PMID: 30421425	c.808G>A	Exon 6	p.Val270Ile	chr6:49612534	rs16879498
4:Null Alleles	Rhnull	RHAG01N.01*	c.154_157delinsGA	Exon 1	p.Pro52Aspfs*57	chr6:49636659
2:Mod Alleles	Rhmod	RHAG01M.01*	c.1183delA	Exon 9	p.Asn395Thrfs*68	chr6:49606877
0:Antigen Alleles	RHAG:1 or Duclos+	RHAG01*
0:Antigen Alleles	RHAG:-1 or Duclos-	RHAG-01*	c.316C>G	Exon 2	p.Gln106Glu	chr6:49619204	rs1180686517
4:Null Alleles	Rhnull	RHAG01N.02*	c.1086delA	Exon 8	p.Ala363Leufs*15	chr6:49607202	rs1562011389
0:Antigen Alleles	RHAG:2 or Ol(a+)	RHAG02*	c.680C>T	Exon 5	p.Ser227Leu	chr6:49614814	rs902283342
2:Mod Alleles	Rhmod	RHAG01M.02*	c.3G>T	Exon 1	p.Arg2_Met8del	chr6:49636810	rs121918588
4:Null Alleles	Rhnull	RHAG01N.03*	c.157+1G>A	Intron 1	Alternative splicing	chr6:49636655	rs375508949
0:Antigen Alleles	RHAG:-3 or DSLK-	RHAG-03*	c.490A>C	Exon 3	p.Lys164Gln	chr6:49618070	rs144305805
2:Mod Alleles	Rhmod	RHAG01M.03*	c.236G>A	Exon 2	p.Ser79Asn	chr6:49619284	rs121918586
2:Mod Alleles	Rhmod	RHAG01M.04*	c.269G>T	Exon 2	p.Gly90Val	chr6:49619251
4:Null Alleles	Rhnull	RHAG01N.04*	c.945+1G>A	Intron 6	Alternative splicing	chr6:49612396
4:Null Alleles	Rhnull	RHAG01N.05*	c.946-1G>A	Intron 6	Alternative splicing	chr6:49611146	rs1562012697
2:Mod Alleles	Rhmod	RHAG01M.05*	c.398T>C	Exon 3	p.Leu133Pro	chr6:49618162
2:Mod Alleles	Rhmod	RHAG01M.06*	c.560G>A	Exon 4	p.Gly187Asp	chr6:49615704
4:Null Alleles	Rhnull	RHAG01N.06*	c.946-1G>T	Intron 6	Alternative splicing	chr6:49611146
2:Mod Alleles	Rhmod	RHAG01M.07*	c.1195G>T	Exon 9	p.Asp399Tyr	chr6:49606865
4:Null Alleles	Rhnull	RHAG01N.07*	c.1067+1G>A	Intron 7	Alternative splicing	chr6:49611023	rs1562012617
2:Mod Alleles	Rhmod	RHAG01M.08*	c.182T>G	Exon 2	p.Ile61Arg	chr6:49619338	rs863225469
4:Null Alleles	Rhnull	RHAG01N.08*	c.808G>A c.838G>A	Exon 6 Exon 6	p.Val270Ile p.Gly280Arg	chr6:49612534 chr6:49612504	rs16879498 rs104893987
2:Mod Alleles	Rhmod	RHAG01M.09*	c.194T>C	Exon 2	p.Phe65Ser	chr6:49619326	rs863225468
4:Null Alleles	Rhnull	RHAG01N.09*	c.836G>A	Exon 6	p.Gly279Glu	chr6:49612506	rs121918587
2:Mod Alleles	Rhmod	RHAG01M.10*	c.572G>A	Exon 4	p.Arg191Gln	chr6:49615692	rs550840907
4:Null Alleles	Rhnull	RHAG01N.10*	c.1094T>G	Exon 8	p.Leu365Arg	chr6:49607194
2:Mod Alleles	Rhmod	RHAG01M.11*	c.241G>C	Exon 2	p.Gly81Arg	chr6:49619279
4:Null Alleles	Rhnull	RHAG01N.11*	c.1139G>T	Exon 9	p.Gly380Val Alternative splicing	chr6:49606921	rs121918589
4:Null Alleles	Rhnull	RHAG01N.12*	c.353C>T	Exon 3	p.Ala118Glu	chr6:49618207
4:Null Alleles	Rhnull	RHAG01N.13*	c.1003G>A	Exon 7	p.Gly335Ser	chr6:49611088	rs976240588
4:Null Alleles	Rhnull	RHAG01N.14*	c.946-2A>G	Intron 6	Alternative splicing	chr6:49611147	rs754264275
4:Null Alleles	Rhnull	RHAG01N.15*	c.(?_-62)_(*638_?)del Gene deletion		p.0
4:Null Alleles	Rhnull	RHAG01N.16*	c.310C>T	Exon 2	p.Gln104*	chr6:49619210	rs1240511011
4:Null Alleles	Rhnull	RHAG01N.17*	c.640+3del14	Exon 4	Alternative splicing	chr6:49615624
4:Null Alleles	Rhnull	RHAG01N.18*	c.790C>T	Exon 5	p.Arg263*	chr6:49614704	rs1397420527