Blood Group Database

004 Rh Blood Group

The Rh blood group system consists of 54 antigens carried on two proteins (RhD and RhCE) each consisting of 417 amino acids. Combinations (hybrids) between the two genes are not uncommon. The proteins consist of 12 membrane-spanning domains.

Antigens

[1] D

[2] C

[3] E

[4] c

[5] e

[6] f

[7] Ce

[8] Cw

[9] Cx

[10] V

[11] Ew

[12] G

[13] …

[14] …

[15] …

[16] …

[17] Hro

[18] Hr

[19] hrS

[20] VS

[21] CG

[22] CE

[23] Dw

[24] …

[25] …

[26] c-like

[27] cE

[28] hrH

[29] Rh29

[30] Goa

[31] hrB

[32] Rh32

[33] Rh33

[34] HrB

[35] Rh35

[36] Bea

[37] Evans

[38] …

[39] Rh39

[40] Tar

[41] Rh41

[42] Rh42

[43] Crawford

[44] Nou

[45] Riv

[46] Sec

[47] Dav

[48] JAL

[49] STEM

[50] FPTT

[51] MAR

[52] BARC

[53] JAHK

[54] DAK

[55] LOCR

[56] CENR

[57] CEST

[58] CELO

[59] CEAG

[60] PARG

[61] CEVF

[62] CEWA

Reference Info

Gene: RHD
Allele: RHD*01
Seq: NG_007494

(genomic), NM_016124

(transcript)
Entrez GeneID: 6007

Number of exons: 10

Gene: RHCE
Allele: RHCE*01 or RHCE*ce, RHCE*02 or RHCE*Ce, RHCE*03 or RHCE*cE, RHCE*04 or RHCE*CE
Seq: NG_009208

(genomic), NM_020485

(transcript)
Entrez GeneID: 6006

Number of exons: 10

RHD
RHCE

Loading Data ...

allele_category	Phenotype	Allele Name	Nucleotide Changes	Exon	Amino Acid Changes	hg38	rsNum
0:Antigen Alleles	D RH:1	RHD01*
3:Null Alleles	Del	RHD01EL.01 RHDDEL1	c.1227G>A	Exon 9	p.Lys409Lys	chr1:25321962	rs549616139
1:Weak Alleles	Type 1	RHD01W.1 RHDweak D type 1	c.809T>G	Exon 6	p.Val270Gly	chr1:25303329	rs121912763
4:Null Alleles	D-	RHD01N.01*	RHD deletion		p.0
0:Antigen Alleles	Normal D antigen	RHD01.01*	c.48G>C	Exon 1	p.Trp16Cys	chr1:25272595	rs772865539
1:Weak Alleles	Type 1.1	RHD01W.1.1 RHDweak D type 1.1	c.52C>G c.809T>G	Exon 1 Exon 6	p.Leu18Val p.Val270Gly	chr1:25272599 chr1:25303329	rs551392307 rs121912763
1:Weak Alleles	Type1.2	RHD01W.1.2 RHDweak D type 1.2	c.712G>A c.809T>G	Exon 5 Exon 6	p.Val238Met p.Val270Gly	chr1:25301597 chr1:25303329	rs1053360 rs121912763
1:Weak Alleles	Type 2	RHD01W.2 RHDweak D type 2	c.1154G>C	Exon 9	p.Gly385Ala	chr1:25321889	rs71652374
0:Antigen Alleles	DII	RHD02 RHDDII	c.1061C>A	Exon 7	p.Ala354Asp	chr1:25306717	rs756982993
3:Null Alleles	Del	RHD01EL.02 RHDDEL2	c.3G>A	Exon 1	p.Met1Ile	chr1:25272550
4:Null Alleles	D-	RHD01N.02*	CE exons 1-9		Hybrid
1:Weak Alleles	Type 2.1	RHD01W.2.1 RHDweak D type 2.1	c.301T>A c.1154G>C	Exon 2 Exon 9	p.Phe101Ile p.Gly385Ala	chr1:25284725 chr1:25321889	rs71652374
1:Weak Alleles	Type2.2	RHD01W.2.2 RHDweak D type 2.2	c.916G>A c.932A>G c.1154G>C	Exon 6 Exon 6 Exon 9	p.Val306Ile p.Tyr311Cys p.Gly385Ala	chr1:25303436 chr1:25303452 chr1:25321889	rs590813 rs590787 rs71652374
3:Null Alleles	Del	RHD01EL.03 RHDDEL3	c.53T>C	Exon 1	p.Leu18Pro	chr1:25272600
1:Weak Alleles	Type 3	RHD01W.3 RHDweak D type 3	c.8C>G	Exon 1	p.Ser3Cys	chr1:25272555	rs144969459
4:Null Alleles	D-	RHD01N.03*	CE exons 2-9		Hybrid
4:Null Alleles	D- C+	RHD03N.01*	c.186G>T c.410C>T c.455A>C CE exons 4-7 with 733C>G 1006G>T	Exon 2	p.Leu62Phe p. Ala137Val p. Asn152Thr hybrid with p.Leu245Val p.Gly336Cys	chr1:25284610	rs199509194
0:Antigen Alleles	DIIIa RH:54 (DAK+)	RHD03.01 RHDDIIIa	c.186G>T c.410C>T c.455A>C c.602C>G c.667T>G c.819G>A	Exon 2 Exon 3 Exon 3 Exon 4 Exon 5 Exon 6	p.Leu62Phe p.Ala137Val p.Asn152Thr p.Thr201Arg p.Phe223Val silent	chr1:25284610 chr1:25290715 chr1:25290760 chr1:25301061 chr1:25301552 chr1:25303339	rs199509194 rs113982491 rs17418085 rs1053355 rs1053356 rs150606530
0:Antigen Alleles	DIIIb Caucasian RH:54 (DAK+) RH:─12 (G─)	RHD03.02 RHDDIIIb	c.150T>C c.178A>C c.201G>A c.203G>A c.307T>C	Exon 2 Exon 2 Exon 2 Exon 2 Exon 2	silent p.Ile60Leu silent p.Ser68Asn p.Ser103Pro	chr1:25284574 chr1:25284602 chr1:25284625 chr1:25284627 chr1:25284731	rs1132758 rs1053341 rs41302032 rs62621068 rs1132760
0:Antigen Alleles	DIIIc	RHD03.03 RHDDIIIc	c.361T>A c.380T>C c.383A>G c.455A>C	Exon 3 Exon 3 Exon 3 Exon 3	p.Leu121Met p.Val127Ala p.Asp128Gly p.Asn152Thr	chr1:25290666 chr1:25290685 chr1:25290688 chr1:25290760	rs41267489 rs201703675 rs758618412 rs17418085
0:Antigen Alleles	DIII type 4	RHD03.04 RHDDIII.04	c.186G>T c.410C>T c.455A>C	Exon 2 Exon 3 Exon 3	p.Leu62Phe p.Ala137Val p.Asn152Thr	chr1:25284610 chr1:25290715 chr1:25290760	rs199509194 rs113982491 rs17418085
0:Antigen Alleles	Not tested	RHD03.04.02 RHDDIII.04.02	c.186G>T c.307T>C c.410C>T c.455A>C	Exon 2 Exon 2 Exon 3 Exon 3	p.Leu62Phe p.Ser103Pro p.Ala137Val p.Asn152Thr	chr1:25284610 chr1:25284731 chr1:25290715 chr1:25290760	rs199509194 rs1132760 rs113982491 rs17418085
0:Antigen Alleles	DIII type 6	RHD03.06 RHDDIII.06	c.410C>T c.455A>C c.602C>G c.667T>G c.819G>A	Exon 3 Exon 3 Exon 4 Exon 5 Exon 6	p.Ala137Val p.Asn152Thr p.Thr201Arg p.Phe223Val silent	chr1:25290715 chr1:25290760 chr1:25301061 chr1:25301552 chr1:25303339	rs113982491 rs17418085 rs1053355 rs1053356 rs150606530
0:Antigen Alleles	DIII type 7 (likely the historically defined DIIIb)	RHD03.07 RHDDIII.07	c.150T>C c.178A>C c.201G>A c.203G>A c.307T>C c.410C>T c.455A>C c.602C>G c.667T>G	Exon 2 Exon 2 Exon 2 Exon 2 Exon 2 Exon 3 Exon 3 Exon 4 Exon 5	silent p.Ile60Leu silent p.Ser68Asn p.Ser103Pro p.Ala137Val p.Asn152Thr p.Thr201Arg p.Phe223Val	chr1:25284574 chr1:25284602 chr1:25284625 chr1:25284627 chr1:25284731 chr1:25290715 chr1:25290760 chr1:25301061 chr1:25301552	rs1132758 rs1053341 rs41302032 rs62621068 rs1132760 rs113982491 rs17418085 rs1053355 rs1053356
0:Antigen Alleles	DIII type 8	RHD03.08 RHDDIII.08	c.410C>T c.455A>C	Exon 3 Exon 3	p.Ala137Val p.Asn152Thr	chr1:25290715 chr1:25290760	rs113982491 rs17418085
0:Antigen Alleles	DIII type 9	RHD03.09 RHDDIII.09	c.186G>T c.410C>T c.455A>C c.667T>G	Exon 2 Exon 3 Exon 3 Exon 5	p.Leu62Phe p.Ala137Val p.Asn152Thr p.Phe223Val	chr1:25284610 chr1:25290715 chr1:25290760 chr1:25301552	rs199509194 rs113982491 rs17418085 rs1053356
1:Weak Alleles	Type3.1	RHD01W.3.1 RHDweak D type 3.1	c.8C>G c.178A>C	Exon 1 Exon 2	p.Ser3Cys p.Ile60Leu	chr1:25272555 chr1:25284602	rs144969459 rs1053341
4:Null Alleles	D-	RHD01N.04*	CE exons 3-9		Hybrid
1:Weak Alleles	Type 4.0, 4.1, 4.2, 4.2.2 weak partial	See partial DAR RHD09.03, 04, 05 RHD*weak partial 4
3:Null Alleles	Del	RHD01EL.04 RHDDEL4	c.147delA	Exon 1	p.Val50Leufs*5	chr1:25272694
0:Antigen Alleles	DIVa RH30+ (Goa+)	RHD04.01 RHDDIVa	c.186G>T c.410C>T c.455A>C c.1048G>C	Exon 2 Exon 3 Exon 3 Exon 7	p.Leu62Phe p.Ala137Val p.Asn152Thr p.Asp350His	chr1:25284610 chr1:25290715 chr1:25290760 chr1:25306704	rs199509194 rs113982491 rs17418085 rs41307826
0:Antigen Alleles	DIVa-like or DIVa type 3	RHD04.01.02*	c.186G>T c.410C>T c.455A>C c.667T>G c.1048G>C	Exon 2 Exon 3 Exon 3 Exon 5 Exon 7	p.Leu62Phe p.Ala137Val p.Asn152Thr p.Phe223Val p.Asp350His	chr1:25284610 chr1:25290715 chr1:25290760 chr1:25301552 chr1:25306704	rs199509194 rs113982491 rs17418085 rs1053356 rs41307826
0:Antigen Alleles	DIV type 3	RHD04.03 RHD* DIV.3*	c.916G>A c.932A>G c.941G>T c.968C>A c.974G>T c.979A>G c.985G>C c.986G>A c.989A>C c.992A>T c.1025T>C c.1048G>C c.1053C>T c.1057G>T c.1059A>G c.1060G>A c.1061C>A c.1063 G>T c.1170T>C c.1193A>T	Exon 6 Exon 6 Exon 7 Exon 7 Exon 7 Exon 7 Exon 7 Exon 7 Exon 7 Exon 7 Exon 7 Exon 7 Exon 7 Exon 7 Exon 7 Exon 7 Exon 7 Exon 7 Exon 9 Exon 9	p.Val306Ile p.Tyr311Cys p.Gly314Val p.Pro323His p.Ser325Ile p.Ile327Val p.Gly329His p.Gly329His p.Tyr330Ser p.Asn331Ile p.Ile343Thr p.Asp350His silent p.Gly353Trp p.Gly353Trp p.Ala354Asn p.Ala354Asn silent silent p.Glu398Val	chr1:25303436 chr1:25303452 chr1:25306597 chr1:25306624 chr1:25306630 chr1:25306635 chr1:25306641 chr1:25306642 chr1:25306645 chr1:25306648 chr1:25306681 chr1:25306704 chr1:25306709 chr1:25306713 chr1:25306715 chr1:25306716 chr1:25306717 chr1:25306719 chr1:25321905 chr1:25321928	rs590813 rs590787 rs200762372 rs200415166 rs780001468 rs751746562 rs755177266 rs138235491 rs41307826 rs41300142 rs200307239 rs1468536305 rs753613761 rs756982993 rs1132772 rs45549244
0:Antigen Alleles	DIV type 4	RHD04.04 RHDDIV.4	c.1048G>C, c.1053C>T c.1057G>T c.1059A>G c.1060G>A c.1061C>A	Intron 7 Exon 7 Exon 7 Exon 7 Exon 7	p.Asp350His silent p.Gly353Trp p.Gly353Trp p.Ala354Asn p.Ala354Asn	chr1:25307757 chr1:25306713 chr1:25306715 chr1:25306716 chr1:25306717	rs1215979107 rs200307239 rs1468536305 rs753613761 rs756982993
0:Antigen Alleles	DIV type 5	RHD04.05 RHDDIV.5	c.941G>T c.968C>A c.974G>T c.979A>G c.985G>C c.986G>A c.989A>C c.992A>T c.1025T>C c.1048G>C c.1053C>T c.1057G>T c.1059A>G c.1060G>A c.1061C>A c.1063G>T c.1170T>C c.1193A>T	Exon 7 Exon 7 Exon 7 Exon 7 Exon 7 Exon 7 Exon 7 Exon 7 Exon 7 Exon 7 Exon 7 Intron 7 Exon 7 Exon 7 Exon 7 Exon 9 Exon 9	p.Gly314Val p.Pro323His p.Ser325Ile p.Ile327Val p.Gly329His p.Gly329His p.Tyr330Ser p.Asn331Ile p. Ile342Thr p.Asp350His silent p.Gly353Trp p.Gly353Trp p.Ala354Asn p.Ala354Asn silent silent p.Glu398Val	chr1:25306597 chr1:25306624 chr1:25306630 chr1:25306635 chr1:25306641 chr1:25306642 chr1:25306645 chr1:25306648 chr1:25306681 chr1:25306704 chr1:25306709 chr1:25307772 chr1:25306716 chr1:25306717 chr1:25306719 chr1:25321905 chr1:25321928	rs200762372 rs200415166 rs780001468 rs751746562 rs755177266 rs138235491 rs41307826 rs41300142 rs1333746082 rs753613761 rs756982993 rs1132772 rs45549244
0:Antigen Alleles	DIVb	RHD04.06 RHDDIVb	c.1048G>C c.1053C>T c.1057G>T c.1059A>G c.1060G>A c.1061C>A c.1170T>C c.1193A>T	Exon 7 Exon 7 Exon 7 Exon 7 Exon 7 Exon 7 Exon 9 Exon 9	p.Asp350His silent p.Gly353Trp p.Gly353Trp p.Ala354Asn p.Ala354Asn silent p.Glu398Val	chr1:25306704 chr1:25306709 chr1:25306713 chr1:25306715 chr1:25306716 chr1:25306717 chr1:25321905 chr1:25321928	rs41307826 rs41300142 rs200307239 rs1468536305 rs753613761 rs756982993 rs1132772 rs45549244
4:Null Alleles	D-	RHD01N.05*	CE exons 2-7		Hybrid
3:Null Alleles	Del	RHD01EL.05 RHDDEL5	c.148+1G>A	Intron 1	Splice site mutation	chr1:25272696
1:Weak Alleles	Type 5	RHD01W.5 RHDweak D type 5	c.446C>A	Exon 3	p.Ala149Asp	chr1:25290751	rs775336070
0:Antigen Alleles	DV type 1	RHD05.01 RHDDV.1	c.667T>G c.697G>C	Exon 5 Exon 5	p.Phe223Val p.Glu233Gln	chr1:25301552 chr1:25301582	rs1053356 rs1053359
0:Antigen Alleles	DV type 2	RHD05.02 RHDDV.2	c.667T>G c.697G>C c.712G>A c.733G>C c.744C>T c.787G>A c.800A>T	Exon 5 Exon 5 Exon 5 Exon 5 Exon 5 Exon 5 Exon 5	p.Phe223Val p.Glu233Gln p.Val238Met p.Val245Leu silent p.Gly263Arg p.Lys267Met	chr1:25301552 chr1:25301582 chr1:25301597 chr1:25301618 chr1:25301629 chr1:25301672 chr1:25301685	rs1053356 rs1053359 rs1053360 rs150073306 rs1053362 rs3118454 rs112907722
0:Antigen Alleles	DV type 3	RHD05.03 RHDDV.3	c.667T>G c.676G>C c.697G>C c.712G>A	Exon 5 Exon 5 Exon 5 Exon 5	p.Phe223Val p.Ala226Pro p.Glu233Gln p.Val238Met	chr1:25301552 chr1:25301561 chr1:25301582 chr1:25301597	rs1053356 rs3193872 rs1053359 rs1053360
0:Antigen Alleles	DV Type 4 RH:23 (Dw+)	RHD05.04 RHDDV.4	c.697G>C	Exon 5	p.Glu233Gln	chr1:25301582	rs1053359
0:Antigen Alleles	DV type 5 RH:-23 (Dw-)	RHD05.05 RHDDV.5	c.697G>A	Exon 5	p.Glu233Lys	chr1:25301582	rs1053359
0:Antigen Alleles	DV type 6	RHD05.06 RHDDV.6	c.667T>G c.697G>C c.712G>A	Exon 5 Exon 5 Exon 5	p.Phe223Val p.Glu233Gln p.Val238Met	chr1:25301552 chr1:25301582 chr1:25301597	rs1053356 rs1053359 rs1053360
0:Antigen Alleles	DV type 7	RHD05.07 RHDDV.7	c.667T>G c.697G>C c.712G>A c.733G>C c.744C>T c.787G>A	Exon 5 Exon 5 Exon 5 Exon 5 Exon 5 Exon 5	p.Phe223Val p.Glu233Gln p.Val238Met p.Val245Leu p.Gly263Arg silent p.Gly263Arg	chr1:25301552 chr1:25301582 chr1:25301597 chr1:25301618 chr1:25301629 chr1:25301672	rs1053356 rs1053359 rs1053360 rs150073306 rs1053362 rs3118454
0:Antigen Alleles	DV type 8	RHD05.08 RHDDV.8	c.667T>G c.697G>C c.712G>A c.733G>C c.744C>T	Exon 5 Exon 5 Exon 5 Exon 5 Exon 5	p.Phe223Val p.Glu233Gln p.Val238Met p.Val245Leu silent	chr1:25301552 chr1:25301582 chr1:25301597 chr1:25301618 chr1:25301629	rs1053356 rs1053359 rs1053360 rs150073306 rs1053362
0:Antigen Alleles	DV type 9	RHD05.09 RHDDV.9	c.697G>C c.712G>A	Exon 5 Exon 5	p.Glu233Gln p.Val238Met	chr1:25301582 chr1:25301597	rs1053359 rs1053360
0:Antigen Alleles	DV type 10	RHD05.10 RHDDV.10	c.667T>G c.697G>C c.712G>A c.733G>C c.744C>T c.787G>A c.800A>T c.916G>A c.932A>G	Exon 5 Exon 5 Exon 5 Exon 5 Exon 5 Exon 5 Exon 5 Exon 6 Exon 6	p.Phe223Val p.Glu233Gln p.Val238Met p.Val245Leu silent p.Gly263Arg p.Lys267Met p.Val306Ile p.Tyr311Cys	chr1:25301552 chr1:25301582 chr1:25301597 chr1:25301618 chr1:25301629 chr1:25301672 chr1:25301685 chr1:25303436 chr1:25303452	rs1053356 rs1053359 rs1053360 rs150073306 rs1053362 rs3118454 rs112907722 rs590813 rs590787
3:Null Alleles	Del or weak D	RHD01EL.06 RHDDEL6	c.251T>C	Exon 2	p.Leu84Pro	chr1:25284675
1:Weak Alleles	Type 6	RHD01W.6 RHDweak D type 6	c.29G>A	Exon 1	p.Arg10Gln	chr1:25272576	rs768456998
4:Null Alleles	D- C+ very weak	RHD01N.06*	CE exons 4-7 with 733C>G 1006G>T	Exon 1	Hybrid with p.Leu245Val p.Gly336Cys	chr1:25272551
0:Antigen Alleles	DVI type 1 RH:─52 (BARC─)	RHD06.01 RHDDVI.1	c.505A>C c.509T>G c.514A>T c.544T>A c.577G>A c.594A>T c.602C>G c.667T>G c.676G>C c.697G>C c.712G>A c.733G>C c.744C>T c.787G>A c.800A>T	Exon 4 Exon 4 Exon 4 Exon 4 Exon 4 Exon 4 Exon 4 Exon 5 Exon 5 Exon 5 Exon 5 Exon 5 Exon 5 Exon 5 Exon 5	p.Met169Leu p.Met170Arg p.Ile172Phe p.Ser182Thr p.Glu193Lys p.Lys198Asn p.Thr201Arg p.Phe223Val p.Ala226Pro p.Glu233Gln p.Val238Met p.Val245Leu silent p.Gly263Arg p.Lys267Met	chr1:25300964 chr1:25300968 chr1:25300973 chr1:25301003 chr1:25301036 chr1:25301053 chr1:25301061 chr1:25301552 chr1:25301561 chr1:25301582 chr1:25301597 chr1:25301618 chr1:25301629 chr1:25301672 chr1:25301685	rs17421137 rs17421144 rs17421151 rs17421158 rs1053352 rs569974439 rs1053355 rs1053356 rs3193872 rs1053359 rs1053360 rs150073306 rs1053362 rs3118454 rs112907722
0:Antigen Alleles	DVI type 2 RH:52 (BARC+)	RHD06.02 RHDDVI.2	c.505A>C c.509T>G c.514A>T c.544T>A c.577G>A c.594A>T c.602C>G c.667T>G c.697G>C c.712G>A c.733G>C c.744C>T c.787G>A c.800A>T c.916G>A c.932A>G	Exon 4 Exon 4 Exon 4 Exon 4 Exon 4 Exon 4 Exon 4 Exon 5 Exon 5 Exon 5 Exon 5 Exon 5 Exon 5 Exon 5 Exon 6 Exon 6	p.Met169Leu p.Met170Arg p.Ile172Phe p.Ser182Thr p.Glu193Lys p.Lys198Asn p.Thr201Arg p.Phe223Val p.Glu233Gln p.Val238Met p.Val245Leu silent p.Gly263Arg p.Lys267Met p.Val306Ile p.Tyr311Cys	chr1:25300964 chr1:25300968 chr1:25300973 chr1:25301003 chr1:25301036 chr1:25301053 chr1:25301061 chr1:25301552 chr1:25301582 chr1:25301597 chr1:25301618 chr1:25301629 chr1:25301672 chr1:25301685 chr1:25303436 chr1:25303452	rs17421137 rs17421144 rs17421151 rs17421158 rs1053352 rs569974439 rs1053355 rs1053356 rs1053359 rs1053360 rs150073306 rs1053362 rs3118454 rs112907722 rs590813 rs590787
0:Antigen Alleles	DVI type 3 RH:52 BARC+	RHD06.03.01 RHDDVI.3	c.361T>A c.380T>C c.383A>G c.455A>C c.505A>C c.509T>G c.514A>T c.544T>A c.577G>A c.594A>T c.602C>G c.667T>G c.697G>C c.712G>A c.733G>C c.744C>T c.787G>A c.800A>T c.916G>A c.932A>G	Exon 3 Exon 3 Exon 3 Exon 3 Exon 4 Exon 4 Exon 4 Exon 4 Exon 4 Exon 4 Exon 4 Exon 5 Exon 5 Exon 5 Exon 5 Exon 5 Exon 5 Exon 5 Exon 6 Exon 6	p.Leu121Met p.Val127Ala p.Asp128Gly p.Asn152Thr p.Met169Leu p.Met170Arg p.Ile172Phe p.Ser182Thr p.Glu193Lys p.Lys198Asn p.Thr201Arg p.Phe223Val p.Glu233Gln p.Val238Met p.Val254Leu silent p.Gly263Arg p.Lys267Met p.Val306Ile p.Tyr311Cys	chr1:25290666 chr1:25290685 chr1:25290688 chr1:25290760 chr1:25300964 chr1:25300968 chr1:25300973 chr1:25301003 chr1:25301036 chr1:25301053 chr1:25301061 chr1:25301552 chr1:25301582 chr1:25301597 chr1:25301618 chr1:25301629 chr1:25301672 chr1:25301685 chr1:25303436 chr1:25303452	rs41267489 rs201703675 rs758618412 rs17418085 rs17421137 rs17421144 rs17421151 rs17421158 rs1053352 rs569974439 rs1053355 rs1053356 rs1053359 rs1053360 rs150073306 rs1053362 rs3118454 rs112907722 rs590813 rs590787
0:Antigen Alleles	DVI type 3.2 BARC not tested	RHD06.03.02 RHDDVI.03.02	c.361T>A c.380T>C c.383A>G c.455A>C c.505A>C c.509T>G c.514A>T c.544T>A c.577G>A c.594A>T c.602C>G c.667T>G c.697G>C c.712G>A c.733G>C c.744C>T c.787G>A c.800A>T c.916G>A c.932A>G c.1195G>A	Exon 3 Exon 3 Exon 3 Exon 3 Exon 4 Exon 4 Exon 4 Exon 4 Exon 4 Exon 4 Exon 4 Exon 5 Exon 5 Exon 5 Exon 5 Exon 5 Exon 5 Exon 5 Exon 6 Exon 6 Exon 9	p.Leu121Met p.Val127Ala p.Asp128Gly p.Asn152Thr p.Met169Leu p.Met170Arg p.Ile172Phe p.Ser182Thr p.Glu193Lys p.Lys198Asn p.Thr201Arg p.Phe223Val p.Glu233Gln p.Val238Met p.Val254Leu silent p.Gly263Arg p.Lys267Met p.Val306Ile p.Tyr311Cys p.Ala399Thr	chr1:25290666 chr1:25290685 chr1:25290688 chr1:25290760 chr1:25300964 chr1:25300968 chr1:25300973 chr1:25301003 chr1:25301036 chr1:25301053 chr1:25301061 chr1:25301552 chr1:25301582 chr1:25301597 chr1:25301618 chr1:25301629 chr1:25301672 chr1:25301685 chr1:25303436 chr1:25303452 chr1:25321930	rs41267489 rs201703675 rs758618412 rs17418085 rs17421137 rs17421144 rs17421151 rs17421158 rs1053352 rs569974439 rs1053355 rs1053356 rs1053359 rs1053360 rs150073306 rs1053362 rs3118454 rs112907722 rs590813 rs590787 rs150059028
0:Antigen Alleles	DVI type 4 RH:52 (BARC+)	RHD06.04 RHDDVI.4	c.361T>A c.380T>C c.383A>G c.455A>C c.505A>C c.509T>G c.514A>T c.544T>A c.577G>A c.594A>T c.602C>G c.667T>G c.697G>C c.712G>A c.733G>C c.744C>T c.787G>A c.800A>T	Exon 3 Exon 3 Exon 3 Exon 3 Exon 4 Exon 4 Exon 4 Exon 4 Exon 4 Exon 4 Exon 4 Exon 5 Exon 5 Exon 5 Exon 5 Exon 5 Exon 5 Exon 5	p.Leu121Met p.Val127Ala p.Asp128Gly p.Asn152Thr p.Met169Leu p.Met170Arg p.Ile172Phe p.Ser182Thr p.Glu193Lys p.Lys198Asn p.Thr201Arg p.Phe223Val p.Glu233Gln p.Val238Met p.Val245Leu silent p.Gly263Arg p.Lys267Met	chr1:25290666 chr1:25290685 chr1:25290688 chr1:25290760 chr1:25300964 chr1:25300968 chr1:25300973 chr1:25301003 chr1:25301036 chr1:25301053 chr1:25301061 chr1:25301552 chr1:25301582 chr1:25301597 chr1:25301618 chr1:25301629 chr1:25301672 chr1:25301685	rs41267489 rs201703675 rs758618412 rs17418085 rs17421137 rs17421144 rs17421151 rs17421158 rs1053352 rs569974439 rs1053355 rs1053356 rs1053359 rs1053360 rs150073306 rs1053362 rs3118454 rs112907722
1:Weak Alleles	Type 7	RHD01W.7 RHDweak D type 7	c.1016G>A	Exon 7	p.Gly339Glu	chr1:25306672
4:Null Alleles	D-G+	RHD01N.07*	CE exons 4-7		Hybrid
3:Null Alleles	Del or weak D	RHD01EL.07 RHDDEL7	c.410C>A	Exon 3	p.Ala137Glu	chr1:25290715
0:Antigen Alleles	DVII RH:40 (Tar+)	RHD07.01 RHDDVII.1	c.329T>C	Exon 2	p.Leu110Pro	chr1:25284753	rs121912762
0:Antigen Alleles	DVII type 2	RHD07.02 RHDDVII.2	c.307T>C c.329T>C	Exon 2 Exon 2	p.Ser103Pro p.Leu110Pro	chr1:25284731 chr1:25284753	rs1132760 rs121912762
1:Weak Alleles	Type 8	RHD01W.8 RHDweak D type 8	c.919G>A	Exon 6	p.Gly307Arg	chr1:25303439	rs762881746
4:Null Alleles	D-	RHD08N.01 RHDPseudo gene RHD Ψ*	37- bp insertion c.609G>A c.654G>C c.667T>G c.674C>T c.807T>G	Exon 5 Exon 5 Exon 5 Exon 6	p.0	chr1:25271975 chr1:25301539 chr1:25301552 chr1:25301559 chr1:25303327	rs141540728 rs1053356 rs148014996 rs141833592
4:Null Alleles	D-	RHD01N.08*	c.48G>A	Exon 1	p.Trp16*	chr1:25272595	rs772865539
3:Null Alleles	Del	RHD01EL.08 RHDDEL8	c.486+1G>A	Intron 3	Splice site mutation	chr1:25290792	rs149598033
0:Antigen Alleles	DFV	RHD08.01 RHDDFV	c.667T>G	Exon 5	p.Phe223Val	chr1:25301552	rs1053356
4:Null Alleles	D-	RHD01N.09*	c.121C>T c.643T>C c.646T>C c.988T>C	Exon 1 Exon 5 Exon 5 Exon 7	p.Gln41Ter	chr1:25272668 chr1:25301528 chr1:25301531 chr1:25306644
1:Weak Alleles	Type 9	RHD01W.9 RHDweak D type 9	c.880G>C	Exon 6	p.Ala294Pro	chr1:25303400
3:Null Alleles	Del or D negative	RHD01EL.09 RHDDEL9	c.486+2T>A	Intron 3	Splice site mutation	chr1:25290793	rs1307580717
0:Antigen Alleles	DAR1 (weak D 4.2)	RHD09.01.00 RHDDAR1.00	c.602C>G c.667T>G c.1025T>C	Exon 4 Exon 5 Exon 7	p.Thr201Arg p.Phe223Val p.Ile342Thr	chr1:25301061 chr1:25301552 chr1:25306681	rs1053355 rs1053356 rs138235491
0:Antigen Alleles	DAR(T203A)	RHD09.01 RHDDAR	c.602C>G c.607A>G c.667T>G c.744C>T c.957G>A c.1025T>C	Exon 4 Exon 4 Exon 5 Exon 5 Exon 7 Exon 7	p.Thr201Arg p.Thr203Ala p.Phe223Val silent silent p.Ile342Thr	chr1:25301061 chr1:25301066 chr1:25301552 chr1:25301629 chr1:25306613 chr1:25306681	rs1053355 rs1053356 rs1053362 rs146292192 rs138235491
0:Antigen Alleles	DAR1.1 (weak D 4.2.1)	RHD09.01.01 RHDDAR1.01	c.602C>G c.667T>G c.957G>A c.1025T>C	Exon 4 Exon 5 Exon 7 Exon 7	p.Thr201Arg p.Phe223Val silent p.Ile342Thr	chr1:25301061 chr1:25301552 chr1:25306613 chr1:25306681	rs1053355 rs1053356 rs146292192 rs138235491
0:Antigen Alleles	DAR1.2 (weak D 4.2.2)	RHD09.01.02 RHDDAR1.02	c.602C>G c.667T>G c.744C>T c.957G>A c.1025T>C	Exon 4 Exon 5 Exon 5 Exon 7 Exon 7	p.Thr201Arg p.Phe223Val silent silent p.Ile342Thr	chr1:25301061 chr1:25301552 chr1:25301629 chr1:25306613 chr1:25306681	rs1053355 rs1053356 rs1053362 rs146292192 rs138235491
0:Antigen Alleles	DAR1.3 (weak D 4.2.3)	RHD09.01.03 RHDDAR1.03	c.602C>G c.667T>G c.744C>T c.1025T>C	Exon 4 Exon 5 Exon 5 Exon 7	p.Thr201Arg p.Phe223Val silent p.Ile342Thr	chr1:25301061 chr1:25301552 chr1:25301629 chr1:25306681	rs1053355 rs1053356 rs1053362 rs138235491
0:Antigen Alleles	DAR2 (DARE)	RHD09.02.00 RHDDAR2.00	c.602C>G c.667T>G c.697G>C c.957G>A c.1025T>C	Exon 4 Exon 5 Exon 5 Exon 7 Exon 7	p.Thr201Arg p.Phe223Val p.Glu233Gln silent p.Ile342Thr	chr1:25301061 chr1:25301552 chr1:25301582 chr1:25306613 chr1:25306681	rs1053355 rs1053356 rs1053359 rs146292192 rs138235491
0:Antigen Alleles	DAR2.1	RHD09.02.01 RHDDAR2.01	c.602C>G c.667T>G c.697G>C c.744C>T c.957G>A c.1025T>C	Exon 4 Exon 5 Exon 5 Exon 5 Exon 7 Exon 7	p.Thr201Arg p.Phe223Val p.Glu233Gln silent silent p.Ile342Thr	chr1:25301061 chr1:25301552 chr1:25301582 chr1:25301629 chr1:25306613 chr1:25306681	rs1053355 rs1053356 rs1053359 rs1053362 rs146292192 rs138235491
0:Antigen Alleles	DAR3 (weak partial D 4.0.1)	RHD09.03 RHDDAR3	c.602C>G c.667T>G	Exon 4 Exon 5	p.Thr201Arg p.Phe223Val	chr1:25301061 chr1:25301552	rs1053355 rs1053356
0:Antigen Alleles	DAR3.1 (weak partial D 4.0)	RHD09.03.01 RHDDAR3.01	c.602C>G c.667T>G c.819G>A	Exon 4 Exon 5 Exon 6	p.Thr201Arg p.Phe223Val silent	chr1:25301061 chr1:25301552 chr1:25303339	rs1053355 rs1053356 rs150606530
0:Antigen Alleles	DAR4 (weak D 4.1)	RHD09.04 RHDDAR4	c.48G>C c.602C>G c.667T>G c.819G>A	Exon 1 Exon 4 Exon 5 Exon 6	p.Trp16Cys p.Thr201Arg p.Phe223Val silent	chr1:25272595 chr1:25301061 chr1:25301552 chr1:25303339	rs772865539 rs1053355 rs1053356 rs150606530
0:Antigen Alleles	DAR5 (weak D 4.3 or Del)	RHD09.05 RHDDAR5	c.602C>G c.667T>G c.819G>A c.872C>G	Exon 4 Exon 5 Exon 6 Exon 6	p.Thr201Arg p.Phe223Val silent p.Pro291Arg	chr1:25301061 chr1:25301552 chr1:25303339 chr1:25303392	rs1053355 rs1053356 rs150606530 rs778406196
0:Antigen Alleles	DAR6 Or DAR(CE2:V50V S68N)	RHD09.06 RHDDAR6 Or RHD09.06 RHDDAR(CE2 :V50V-S68N)	c.150T>C c.178A>C c.201G>A c.203G>A c.602C>G c.667T>G c.1025T>C	Exon 2 Exon 2 Exon 2 Exon 2 Exon 4 Exon 5 Exon 7	silent p.Ile60Leu silent p.Ser68Asn p.Thr201Arg p.Phe223Val p.Ile342Thr	chr1:25284574 chr1:25284602 chr1:25284625 chr1:25284627 chr1:25301061 chr1:25301552 chr1:25306681	rs1132758 rs1053341 rs41302032 rs62621068 rs1053355 rs1053356 rs138235491
1:Weak Alleles	Type 10	RHD01W.10 RHDweak D type 10	c.1177T>C	Exon 9	p.Trp393Arg	chr1:25321912	rs201345482
4:Null Alleles	D-	RHD01N.10*	c.270G>A	Exon 2	p.Trp90*	chr1:25284694
0:Antigen Alleles	DAU0	RHD10.00 RHDDAU0	c.1136C>T	Exon 8	p.Thr379Met	chr1:25317062	rs61740966
3:Null Alleles	Del	RHD01EL.10 RHDDEL10	c.1222T>C	Exon 9	p.Trp408Arg	chr1:25321957
0:Antigen Alleles	DAU0.01	RHD10.00.01 RHDDAU0.01	c.1136C>T c.579G>A	Exon 4 Exon 8	p.Thr379Met silent	chr1:25301038 chr1:25317062	rs77813628 rs61740966
0:Antigen Alleles	DAU0.02	RHD10.00.02 RHDDAU0.02	c.1136C>T c.150T>C	Exon 2 Exon 8	p.Thr370Met Silent(commo n)	chr1:25284574 chr1:25317062	rs1132758 rs61740966
0:Antigen Alleles	DAU1	RHD10.01 RHDDAU1	c.689G>T c.1136C>T	Exon 5 Exon 8	p.Ser230Ile p.Thr379Met	chr1:25301574 chr1:25317062	rs374920252 rs61740966
0:Antigen Alleles	DAU2	RHD10.02 RHDDAU2	c.209G>A c.998G>A c.1136C>T	Exon 2 Exon 7 Exon 8	p.Arg70Gln p.Ser333Asn p.Thr379Met	chr1:25284633 chr1:25306654 chr1:25317062	rs142925159 rs144996388 rs61740966
0:Antigen Alleles	DAU3	RHD10.03 RHDDAU3	c.835G>A c.1136C>T	Exon 6 Exon 8	p.Val279Met p.Thr379Met	chr1:25303355 chr1:25317062	rs139704879 rs61740966
0:Antigen Alleles	DAU4	RHD10.04 RHDDAU4	c.697G>A c.1136C>T	Exon 5 Exon 8	p.Glu233Lys p.Thr379Met	chr1:25301582 chr1:25317062	rs1053359 rs61740966
0:Antigen Alleles	DAU5	RHD10.05 RHDDAU5	c.667T>G c.697G>C c.1136C>T	Exon 5 Exon 5 Exon 8	p.Phe223Val p.Glu233Gln p.Thr379Met	chr1:25301552 chr1:25301582 chr1:25317062	rs1053356 rs1053359 rs61740966
0:Antigen Alleles	DAU5.1	RHD10.05.01 RHDDAU5.01	c.667T>G c.697G>C c.1122C>T c.1136C>T	Exon 5 Exon 5 Exon 8 Exon 8	p.Phe223Val p.Glu233Gln silent p.Thr379Met	chr1:25301552 chr1:25301582 chr1:25317048 chr1:25317062	rs1053356 rs1053359 rs61740966
0:Antigen Alleles	DAU6	RHD10.06 RHDDAU6	c.998G>A c.1136C>T	Exon 7 Exon 8	p.Ser333Asn p.Thr379Met	chr1:25306654 chr1:25317062	rs144996388 rs61740966
0:Antigen Alleles	DAU7	RHD10.07 RHDDAU7	c.835G>A c.998G>A c.1136C>T	Exon 6 Exon 7 Exon 8	p.Val279Met p.Ser333Asn p.Thr379Met	chr1:25303355 chr1:25306654 chr1:25317062	rs139704879 rs144996388 rs61740966
0:Antigen Alleles	DAU8	RHD10.08 RHDDAU8	c.340C>T c.579G>A c.1136C>T	Exon 3 Exon 4 Exon 8	p.Arg114Trp silent p.Thr379Met	chr1:25290645 chr1:25301038 chr1:25317062	rs1170303671 rs77813628 rs61740966
0:Antigen Alleles	DAU9	RHD10.09 RHDDAU9	c.535T>C c.1136C>T	Exon 4 Exon 8	p.Phe179Leu p.Thr379Met	chr1:25300994 chr1:25317062	rs61740966
1:Weak Alleles	Type 10.1	RHD01W.10.1 RHDweak D type 10.1	c.1145T>C c.1177T>C	Exon 8 Exon 9	p.Leu382Pro p.Trp393Arg	chr1:25317071 chr1:25321912	rs201345482
0:Antigen Alleles	DAU10	RHD10.10 RHDDAU10	c.579G>A c.739G>C c.1136C>T	Exon 4 Exon 5 Exon 8	silent p.Val247Leu p.Thr379Met	chr1:25301038 chr1:25301624 chr1:25317062	rs77813628 rs61740966
0:Antigen Alleles	DAU11	RHD10.11 RHDDAU11	c.254C>T c.835G>A c.1136C>T	Exon 2 Exon 6 Exon 8	p.Ala85Val p.Val279Met p.Thr379Met	chr1:25284678 chr1:25303355 chr1:25317062	rs139501061 rs139704879 rs61740966
0:Antigen Alleles	DAU12	RHD10.12 RHDDAU12	c.542T>C c.1136C>T	Exon 4 Exon 8	p.Leu181Pro p.Thr379Met	chr1:25301001 chr1:25317062	rs149700508 rs61740966
0:Antigen Alleles	DAU13	RHD10.13 RHDDAU13	c.48G>C c.1136C>T	Exon 1 Exon 8	p.Trp16Cys p.Thr379Met	chr1:25272595 chr1:25317062	rs772865539 rs61740966
0:Antigen Alleles	DAU14	RHD10.14 RHDDAU14	c.201G>A c.203G>A c.1136C>T	Exon 2 Exon 2 Exon 8	silent p.Ser68Asn p.Thr379Met	chr1:25284625 chr1:25284627 chr1:25317062	rs41302032 rs62621068 rs61740966
0:Antigen Alleles	RHD(M1V,T379M ) Or DAU15	RHD10.15 RHDDAU15 Or RHD10.15	c.1A>G c.1136C>T	Exon 1 Exon 8	p.Met1Val p.Thr379Met	chr1:25272548 chr1:25317062	rs61740966
1:Weak Alleles	Type 10.2	RHD01W.10.2 RHDweak D type 10.2	c.1177T>C c.1199A>C	Exon 9 Exon 9	p.Trp393Arg p.Lys400Thr	chr1:25321912 chr1:25321934	rs201345482
0:Antigen Alleles	Type 11 weak partial or Del phenotype	See partial RHD11*	c.885G>T	Exon 6	p.Met295Ile	chr1:25303405	rs371803235
4:Null Alleles	D-	RHD01N.11*	c.325delA	Exon 2	p.Thr109Hisfs*10	chr1:25284749
0:Antigen Alleles	weak partial 11 or Del	RHD11 RHDweak partial 11	c.885G>T	Exon 6	p.Met295Ile	chr1:25303405	rs371803235
3:Null Alleles	Del	RHD01EL.11 RHDDEL11	c.1252_1253insT	Exon 10	p.418Leuext71	chr1:25328922
4:Null Alleles	D-	RHD01N.12*	c.449delT	Exon 3	p.Leu150*	chr1:25290754
1:Weak Alleles	Type 12	RHD01W.12 RHDweak D type 12	c.830G>A	Exon 6	p.Gly277Glu	chr1:25303350	rs1557543876
3:Null Alleles	Del	RHD01EL.12 RHDDEL12	c.458T>C	Exon 3	p.Leu153Pro	chr1:25290763
0:Antigen Alleles	DOL1 RH:54(DAK+)	RHD12.01 RHDDOL1	c.509T>C c.667T>G	Exon 4 Exon 5	p.Met170Thr p.Phe223Val	chr1:25300968 chr1:25301552	rs17421144 rs1053356
0:Antigen Alleles	DOL2 RH:54(DAK+)	RHD12.02 RHDDOL2	c.509T>C c.667T>G c.1132C>G	Exon 4 Exon 5 Exon 8	p.Met170Thr p.Phe223Val p.Leu378Val	chr1:25300968 chr1:25301552 chr1:25317058